What is the most appropriate way to address an elderly woman named Genevieve Nesmith?

Using "Mrs. Nesmith" is the most appropriate way to address an elderly woman, particularly in a formal or professional context. This title conveys respect and recognizes her marital status, which is traditionally represented by "Mrs." when addressing a married woman. It acknowledges her as a mature adult, suitable for the setting in which a health professional may interact with patients.

While using her first name, "Genevieve," may feel friendly, it is usually more appropriate to use formal titles when first meeting someone, especially in healthcare settings. Addressing her as "Ms. Nesmith" is also a respectful option, but "Mrs." specifically indicates the understanding that she is married. The title "Aunt Genevieve" implies a personal relationship that may not exist, which can be seen as overly familiar or informal in a professional encounter.